Pastorates have included the Metropolitan Bible Church in Ottawa, Ontario, Canada, and Forward Baptist Church in Cambridge, Ontario, Canada. He was installed as Senior Pastor of the historic Calvary Baptist Church in New York City on February 8, 1998.

In addition to Pastor Epstein's teaching ministry, leadership development, and focus on outreach and evangelism, his pastorates have included radio broadcast, and spiritual life and prophetic conferences in North America, Israel, India and Greece. He served as the President of the Ottawa Evangelical Ministerium from 1989-1991. In October, 1997, he received the Washington Bible College Alumnus of the Year award for "Outstanding Spiritual Character and Accomplishment in the Service of the Lord." Along with tending the flock, he is host of the popular radio broadcast, Tell It From Calvary which airs six days a week in New York City.

Pastor Epstein enjoys an occasional game of golf when time permits. He and his wife Sandy are blessed with three married children and seven beautiful grandchildren.